Steven Austad
饰：Himself - University of Alabama at Birmingham, Department of Bio
Nir Barzilai
饰：Himself - Albert Einstein College of Medicine
安吉拉·贝塞特
Angela Bassett
饰：Herself
杰森·贝特曼
Jason Bateman
饰：Narrator
彼得·博格
Peter Berg
饰：Narrator
Lynn Black
饰：Herself - Last Mile Health - Liberia, Massachusetts General Hosp
Tsenai Bogale
饰：Himself
Christopher James Bohinski
饰：Study participant
阿德里安·布劳迪
Adrien Brody
饰：Narrator
Sarah Crane
饰：Herself - Geriatrician, Mayo Clinic
Ian Crozier
饰：Himself
Laura Deming
饰：Herself - Venture Capitalist, Biologist
John M. Dye
饰：Himself - Chief of Viral Immunology, USAMRIID
Benjamin Emanuel
饰：Himself
Ezekiel Emanuel
饰：Himself - UPenn Department of Medical Ethics and Health Policy
Jonathan Fiévez
饰：Himself
保罗·吉亚玛提
Paul Giamatti
饰：Himself
Fiona Ginty
饰：Herself - GE Global Research Center
Tadessa Girmay
饰：Himself
Rita Golomb
饰：Herself
Beati Guevara
饰：Himself
朗·霍华德
Ron Howard
饰：Narrator
Edward Kamin
饰：Himself - 84 years old
Martha Kamin
饰：Herself - 90 years old
Brima Kargbo
饰：Himself - Chief Medical Officer, Sierra Leone
James L. Kirkland
饰：Himself - Geriatrician, Mayo Clinic
Stephanie Lederman
饰：Herself - American Federation for Aging Research
Gordon J. Lithgow
饰：Himself - Buck Institute for Research on Aging
Aaron Mandell
饰：Himself
Joan Mannick
饰：Herself - Novartis Institutes for Biomedical Research
Simon Melov
饰：Himself - Buck Institute for Research on Aging
Andy Mercer
饰：Himself
Milton Nussdorf
饰：Himself
Erica Ollmann Saphire
饰：Herself - Professor
Jay Olshansky
饰：Himself - University of Illinois at Chicago
Matt Stuber
饰：Himself
Robert Temple
饰：Himself - Deputy Director, FDA
Tanya Thompson
饰：Woman 1
Alessandro Vespignani
饰：Himself - Professor, Northeastern University
Arturo Vittori
饰：Himself
Cindy Wallis-Lage
饰：Herself
Sarah Wolfe
饰：Herself
小艾德·博格里
Ed Begley Jr.
饰：Nostradamus
Cynthia Kenyon
Cynthia Kenyon
饰：Herself - UCSF School of Medicine, VP Calico
Nate Silver
饰：Himself
Dave Klec
饰：Cell Phone Addict
David Nutt
饰：Himself
Amanda Feilding
饰：Herself
J·K·西蒙斯
J.K. Simmons
饰：Narrator
菲利普·E·沃克
Phillip E. Walker
饰：Ebola Patient
克里斯·派恩
Chris Pine
饰：Narrator
迈克·柯尔特
Mike Colter
希拉·凡德
Sheila Vand
大卫·柯南伯格
David Cronenberg
Claire McCaskill
Claire McCaskill