After super-villains obliterate Chicago in 1976, those Americans fortunate enough to have powers must either work for the US government or go underground. Today, the legendary Patriot leads the rebellious Defiance against his former masters, the sanctioned super-powered operatives known collectively as Delta Prime. When the Primers capture Patriot, his friends must find a way to break into the toughest super-prison ever created-or watch him be executed before the entire world.