托比·马奎尔

Tobey Maguire

饰：蜘蛛侠 / 彼得·帕克 Spider-Man / Peter Parker

克尔斯滕·邓斯特

Kirsten Dunst

饰：简 Mary Jane Watson

威廉·达福

Willem Dafoe

饰：绿魔 Green Goblin / Norman Osborn

詹姆斯·弗兰科

James Franco

饰：哈利 Harry Osborn

克里夫·罗伯逊

Cliff Robertson

饰：本 Ben Parker

罗斯玛丽·哈里斯

Rosemary Harris

饰：梅 May Parker

J·K·西蒙斯

J.K. Simmons

饰：约拿 J. Jonah Jameson

乔·曼根尼罗

Joe Manganiello

饰：费时 Flash Thompson

格里·贝克尔

Gerry Becker

饰：马克西米利安法尔加斯 Maximilian Fargas

比尔·努恩

Bill Nunn

饰：Joseph 'Robbie' Robertson

杰克·贝茨

Jack Betts

饰：Henry Balkan

斯坦利·安德森

Stanley Anderson

饰：General Slocum

罗恩·帕金斯

Ron Perkins

饰：Dr. Mendell Stromm

迈克尔·帕帕约翰

Michael Papajohn

饰：Carjacker

K.K. Dodds

K.K. Dodds

饰：Simkins

泰德·雷米

Ted Raimi

饰：Hoffman

布鲁斯▪坎贝尔

Bruce Campbell

饰：Ring Announcer

伊丽莎白·班克斯

Elizabeth Banks

饰：Betty Brant

蒂姆·德·赞

Tim De Zarn

饰：Philip Watson (as Tim deZarn)

Taylor Gilbert

Taylor Gilbert

饰：Madeline Watson

兰迪·萨瓦格

Randy Savage

饰：Bone Saw McGraw

拉里·约书亚

Lawrence Joshua

饰：Wrestling Promoter

Timothy Patrick Quill

Timothy Patrick Quill

饰：Wrestling Arena Guard

Shan Omar Huey

饰：Teacher

Evan Arnold

Evan Arnold

饰：Doctor

Jill Sayre

饰：Nurse

James Kevin Ward

饰：Project Coordinator (as James K. Ward)

奥克塔维亚·斯宾瑟

Octavia Spencer

饰：Check-In Girl

Johnny Cocktails

Johnny Cocktails

饰：Heckler

黛博拉·沃克汉姆

Deborah Wakeham

饰：Billy's Mom

Mackenzie Bryce

饰：Times Square Child

玛西·格雷

Macy Gray

饰：Herself

迈克·沃特福德

Myk Watford

饰：Cop at Fire

比尔·卡尔弗特

Bill Calvert

饰：Fireman (as William Calvert)

席尔瓦·克莱吉安

Sylva Kelegian

饰：Mother at Fire

阿杰·梅赫塔

Ajay Mehta

饰：Cabbie

彼得·阿佩尔

Peter Appel

饰：Cabbie

斯科特·斯皮格尔

Scott Spiegel

饰：Marine Cop

莎拉·拉米尔兹

Sara Ramirez

饰：Cop at Carjacking

露西·劳莱丝

Lucy Lawless

饰：Punk Rock Girl

杰西·巴托克

Jayce Bartok

饰：Subway Guitarist

乔·多诺弗里奥

Joe D'Onofrio

饰：Opinionated Cop (as Joseph D'Onofrio)

吉姆·诺顿

Jim Norton

饰：Surly Truck Driver

Corey Mendell Parker

Corey Mendell Parker

饰：Chaperone in Tram

阿什丽·艾德纳

Ashley Edner

饰：Girl in Tram (as Ashley Louise Edner)

William Joseph Firth

饰：Boy in Tram

Alex Black

饰：Boy in Tram

Laura Gray

Laura Gray

饰：Tram Group Mother

乔·沃兹

Joe Virzi

饰：New Yorker on Bridge

Michael Edward Thomas

饰：New Yorker on Bridge

罗伯特·科尔曼

Robert Kerman

饰：Tugboat Captain

瑞克·艾弗里

Rick Avery

饰：Cop (uncredited)

Andrew Bernard Wolff

Andrew Bernard Wolff

饰：Boy carrying tray in Cafeteria (uncredited)

约夫里·C·布朗

Jophery C. Brown

饰：Chef (uncredited)

Jacob Chambers

饰：Cop (uncredited)

克里斯·科波拉

Chris Coppola

饰：Kyle (uncredited)

伍娜·戴蒙

Una Damon

饰：Lab Tour Guide (uncredited)

Chandra De Alessandro

饰：Cop (uncredited)

马克·德亚历山德罗

Mark De Alessandro

饰：Cop (uncredited)

Patrick Coleman Duncan

饰：Oscorp Lab Technician (uncredited)

R.C. Everbeck

饰：Eddie Brock (uncredited)

阿尔·后藤

Al Goto

饰：Cop (uncredited)

兰迪·霍尔

Randy Hall

饰：Cop (uncredited)

凯文·杰克逊

Kevin Jackson

饰：Bellman (uncredited)

洛伦·简斯

Loren Janes

饰：Board of Directors Member (uncredited)

安德雷·强森

Andray Johnson

饰：Balkan's Aide (uncredited)

克劳迪娅·卡茨

Claudia Katz

饰：Robbie's Assistant (uncredited)

斯坦·李

Stan Lee

饰：Man in Fair (uncredited)

Pete Macnamara

Pete Macnamara

饰：Pentagon Officer (uncredited)

菲利普·吴

Philip Ng

饰：Diamond District Attendee (uncredited)

Sean Valla

饰：Boat Light Man (uncredited)

Derek C. Wallace

饰：Homeless Man (uncredited)

John Wojnowski III

饰：Man in Street (uncredited)

Sally Livingstone

饰：Girl on Bus

David Holcomb

饰：Test Pilot

Shane Habberstad

饰：Little Billy

Rachael Bruce

饰：Times Square Child

Julia Barry

饰：Times Square Child

Kristen Marie Holly

饰：Young Lady at Fire

Matt Smith

饰：Cop at Carjacking

Maribel González

饰：Lady Dogwalker (as Maribel Gonzalez)

Amy Bouril

Amy Bouril

饰：Office Lady

Jeanie Fox

饰：New Yorker on Bridge

Ari Averbach

饰：Dancer (uncredited)

Joni Avery

饰：Cop (uncredited)

Margaret Baker

饰：Punk #2 (uncredited)

Amy Beth Bennett

饰：Jewelry Thief #2 (uncredited)

Brian Bennett

Brian Bennett

饰：Doorman (uncredited)

Camille Bennett

饰：High School Student (uncredited)

Jillian Clare

饰：Crying Girl in Tram (uncredited)

Cody Cundiff

饰：World Unity Day attendee (uncredited)

Marcus Edward

饰：Screaming Fan at Wrestling Match (uncredited)

Marcus Gorman

饰：Man in Street (uncredited)

Johnny Guerra

Johnny Guerra

饰：City guy (uncredited)

蒂亚·迪昂·霍奇

Tia Dionne Hodge

饰：Uptown Woman (uncredited)

Erik Kleven

饰：Chef (uncredited)

Justin Neill

饰：Flash's Crony (uncredited)

Debra Orenstein

饰：Doctor (uncredited)

Gary Otto

饰：New Yorker (uncredited)

Leroy Patterson

饰：World Unity Festival Attentdant (uncredited)

萨默·雷石东

Sumner Redstone

饰：Oscorp Board Member (uncredited)

Robair Sims

饰：Bellman (uncredited)

林赛·汤普森

Lindsay Thompson

饰：Mary Jane's Friend (uncredited)

Kristen Davidson

饰：Bone-ette

杰森·帕德格特

Jason Padgett

饰：Flash's Crony

Lisa Danielle

饰：Bone-ette

Natalie T. Yeo

饰：Bone-ette

Erica D. Porter

饰：Bone-ette

Scott L. Schwartz

Scott L. Schwartz

饰：Screaming Wrestler (uncredited)

Richard Stephens

饰：Man on Brooklyn Bridge (uncredited)

Tammi Sutton

饰：Street Vendor (uncredited)

Lance Polland

饰：Bonesaw Fan

Andy Bray

饰：Boy Carrying Tray in Cafeteria

杰西·海曼

Jesse Heiman

饰：Spectator at School Fight

布拉德·格伦伯格

Brad Grunberg

饰：Heckler

Joy Michelle Moore

饰：World's Fair Mom

Juan M. Guerra

饰：演员 Actor/Actress

宾尼·尤奎德兹

Benny Urquidez

饰：Mugger

Peter Genovese

饰：Fleeing World Unity Day Patron

金锋

Feng Jin

卢·托雷斯

Lou Torres

饰：Enrique

杰克·贝兹

Jack Betts

饰：Henry Balkan

Sylva Kelegian

Sylva Kelegian

饰：Mother at Fire

Sally Levi

饰：Girl on Bus,(as Sally Livingstone)